[ kroh-muh-tol-uh-sis ]
/ ˌkroʊ məˈtɒl ə sɪs /

noun Cell Biology, Pathology.

the dissolution and disintegration of chromatin.

Origin of chromatolysis

First recorded in 1900–05; chromato- + -lysis

Related forms

chro·mat·o·lyt·ic [kruh-mat-l-it-ik, kroh-muh-tl-it-] /krəˌmæt lˈɪt ɪk, ˌkroʊ mə tlˈɪt-/, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Examples from the Web for chromatolysis

  • Some of the cells of the anterior horn were swollen and the nuclei eccentric; chromatolysis had occurred in many of them.

    Handbook of Medical Entomology|William Albert Riley

British Dictionary definitions for chromatolysis


/ (ˌkrəʊməˈtɒlɪsɪs) /


cytology the dissolution of stained material, such as chromatin in injured cells
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for chromatolysis


[ krō′mə-tŏlĭ-sĭs ]


The disintegration of chromophil substance in a nerve cell body; it may occur after exhaustion of the cell or after damage to its peripheral process.chromolysis

Related forms

chro•mat′o•lytic (-măt′l-ĭtĭk) adj.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.