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Synonyms

cocaine

American  
[koh-keyn, koh-keyn] / koʊˈkeɪn, ˈkoʊ keɪn /

noun

Pharmacology.
  1. a bitter, crystalline alkaloid, C 17 H 21 NO 4 , obtained from coca leaves, used as a local anesthetic and also widely used as an illicit drug for its stimulant and euphorigenic properties.


cocaine British  
/ kəˈkeɪn /

noun

  1. an addictive narcotic drug derived from coca leaves or synthesized, used medicinally as a topical anaesthetic. Formula: C 17 H 21 NO 4

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

cocaine Scientific  
/ kō-kān /
  1. A colorless or white crystalline alkaloid extracted from coca leaves. Cocaine is sometimes used in medicine as a local anesthetic, especially for the eyes, nose, or throat. It is also widely used as an illicit drug for its euphoric and stimulating effects. Chemical formula: C 17 H 21 NO 4 .


cocaine Cultural  
  1. A drug derived from the leaves of a shrub in South America that has an intoxicating effect on the body and can result in dependency if frequently used. Cocaine is used medically as a local anesthetic.


Discover More

Cocaine use constitutes a major drug problem in the United States.

Etymology

Origin of cocaine

First recorded in 1870–75; coca + -ine 1

Vocabulary lists containing cocaine

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Abelardo de la Espriella promises more prisons and a crackdown after cocaine production and the ranks of armed groups expanded across the country.

From The Wall Street Journal Jun. 25, 2026

Researchers at Washington University School of Medicine in St. Louis found that GLP-1 medications were associated with lower risks of developing substance use disorders involving alcohol, nicotine, cannabis, cocaine, opioids, and other substances.

From Science Daily Jun. 3, 2026

US President Donald Trump has made the fight against criminal gangs sending illicit drugs such as heroin, fentanyl, methamphetamines and cocaine one of his priorities.

From BBC Jan. 26, 2026

Seizures of fentanyl at the U.S.-Mexico border have fallen in recent years, while seizures of cocaine have risen.

From Los Angeles Times Jan. 8, 2026

In fact, scientists who study both the brains of new lovers and cocaine addicts are hard-pressed to tell the difference.

From "The Sun Is Also a Star" by Nicola Yoon

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