[ kree-at-n-een, -in ]
/ kriˈæt nˌin, -ɪn /

noun Biochemistry.

a crystalline end product of creatine metabolism, C4H7N3O, occurring in urine, muscle, and blood.



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Origin of creatinine

1850–55; <German Kreatinin, equivalent to kreatincreatine + -in-ine2 Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2020

Example sentences from the Web for creatinine

  • Creatine and creatinine also seem to lessen in amount, but of the extent of this change I am not as yet fully informed.

    Fat and Blood|S. Weir Mitchell
  • The creatinine was estimated in two cases and was found to be 2.0 mg.

    Scurvy Past and Present|Alfred Fabian Hess
  • Foremost among them are uric acid, creatinine, and the coloring-matter.

  • The precipitate contains the picrate of trimethylenediamine, mixed with the picrates of cadaverine and creatinine.

British Dictionary definitions for creatinine

/ (kriːˈætəˌniːn) /


an anhydride of creatine that is abundant in muscle and excreted in the urine

Word Origin for creatinine

C19: from German Kreatinin, from Kreatin creatine + -in -ine ²
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medical definitions for creatinine

[ krē-ătn-ēn′, -ĭn ]


A creatine anhydride formed by the metabolism of creatine and found in muscle tissue and blood and normally excreted in the urine as metabolic waste.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Scientific definitions for creatinine

[ krē-ătn-ēn′, -ĭn ]

A compound formed by the metabolism of creatine, found in muscle tissue and blood and normally excreted in the urine as a metabolic waste. Measurement of creatinine levels in the blood is used to evaluate kidney function. Chemical formula: C4H7N3O.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.