Creutzfeldt-Jakob disease

or Creutz·feldt-Ja·cob disease

[ kroits-felt yah-kawp ]
/ ˈkrɔɪts fɛlt ˈyɑ kɔp /
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noun Pathology.
a rare, usually fatal brain disorder thought to be caused by an infectious prion and characterized by progressive dementia, blindness, and involuntary movements.
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Origin of Creutzfeldt-Jakob disease

1965–70; after German physicians Hans G. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931)

Words nearby Creutzfeldt-Jakob disease

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2022

How to use Creutzfeldt-Jakob disease in a sentence

British Dictionary definitions for Creutzfeldt-Jakob disease

Creutzfeldt-Jakob disease
/ (ˈkrɔɪtsfɛlt ˈjɑːkɒp) /

pathol a fatal slow-developing disease that affects the central nervous system, characterized by mental deterioration and loss of coordination of the limbs. It is thought to be caused by an abnormal prion protein in the brain

Word Origin for Creutzfeldt-Jakob disease

C20: named after Hans G. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931), German physicians
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Scientific definitions for Creutzfeldt-Jakob disease

Creutzfeldt-Jakob disease
[ kroitsfĕlt-yäkôp ]

A rare, usually fatal encephalopathy that occurs most often in middle age and is likely caused by a prion. It is characterized by progressive dementia and gradual loss of muscle control. The disease is named after its discoverers, German pathologist Hans Gerhard Creutzfeldt (1885-1964) and German neurologist Alfons Maria Jakob (1884-1931).
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.