Crohn's disease

[krohnz]

noun

Pathology.

1. a chronic inflammatory bowel disease that causes scarring and thickening of the intestinal walls and frequently leads to obstruction.

Crohn's disease

/ krəʊnz /

noun

1. Also called: regional enteritis. inflammation, thickening, and ulceration of any of various parts of the intestine, esp the ileum See also Johne's disease

Crohn's disease

1. A gastrointestinal disease characterized by inflammation of the ileum, resulting in abdominal cramping, diarrhea, and weight loss. It is named after American physician Burrill Bernard Crohn (1884–1983), who first described it.

Word History and Origins

Origin of Crohn's disease¹

Named after Burrill Bernard Crohn (1884–1983), U.S. physician, one of the authors of a description of the disease published in 1932

Word History and Origins

Origin of Crohn's disease¹

C20: named after B. B. Crohn (1884–1983), US physician

Example Sentences

Discovered in 2001, NOD2 was the first gene linked to an increased risk of Crohn's disease.

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However, the most common Crohn's disease mutation in the NOD2 gene deletes the section where girdin normally binds.

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To confirm their findings, the scientists compared mouse models of Crohn's disease that lacked the girdin protein with those that still had it.

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By merging AI-based analysis, biochemical research, and animal experiments, the study resolves one of the longest-standing questions in Crohn's disease research.

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Her cancer treatment and experience with Crohn's disease have been depicted in the BBC documentaries Strictly Amy: Cancer And Me and Strictly Amy: Crohn's And Me.

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