[ sahy-kluh-spawr-een, -in, -spohr-, sik-luh- ]
/ ˌsaɪ kləˈspɔr in, -ɪn, -ˈspoʊr-, ˌsɪk lə- /

noun Pharmacology.

a substance, synthesized by certain soil fungi, that suppresses the immune response by disabling helper T cells, used to minimize rejection of foreign tissue transplants.

Nearby words

  1. cyclops,
  2. cyclorama,
  3. cyclosilicate,
  4. cyclosis,
  5. cyclosporin,
  6. cyclostomatous,
  7. cyclostome,
  8. cyclostrophic,
  9. cyclostyle,
  10. cyclothyme

Also cy·clo·spo·rin [sahy-kluh-spawr-in, -spohr-, sik-luh-] /ˌsaɪ kləˈspɔr ɪn, -ˈspoʊr-, ˌsɪk lə-/.

Origin of cyclosporine

1975–80; < New Latin Cyclospor(eae) a class of brown algae (see cyclo-, -spore, -eae) + -in2 Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Medicine definitions for cyclosporine


[ sī′klə-spôrēn, -ĭn ]


A cyclic oligopeptide immunosuppressant produced by fungus and used to inhibit organ transplant rejection.

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

Science definitions for cyclosporine


[ sī′klə-spôrēn, -ĭn ]

A polypeptide obtained from any of various deuteromycete fungi, used as an immunosuppressive drug to prevent the rejection of transplanted organs.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.