de novo
Americanadverb
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anew; afresh; again; from the beginning.
We reviewed the court’s decision de novo during the rehearing.
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independently of external forces; from within; spontaneously.
Mutations associated with autism often occur de novo rather than through inheritance.
adjective
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occurring or arising spontaneously or independently of external forces; spontaneous: de novo synthesis of steroids from cholesterol.
de novo mutations;
de novo synthesis of steroids from cholesterol.
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made from scratch rather than developed from or based on something preexisting, and hence new, novel, or of a new type: de novo banks.
de novo protein design;
de novo banks.
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De Novo, noting or related to a type of FDA classification allowing novel medical devices with no precedent on the market to be sold: De Novo classification.
a De Novo request;
De Novo classification.
adverb
Etymology
Origin of de novo
First recorded in 1620–30; from Latin dē novō “anew, afresh, again”
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
World Liberty Trust filed its de novo application Wednesday with the U.S.
Researchers are, therefore, trying to recreate them or to design so-called de novo proteins that do not occur in nature.
From Science Daily
"These de novo or reference-guided assemblers are pretty well-established tools that entail a whole operational pipeline with repeat detection or structural variants' identification being just some of their functionalities," Segarra said.
From Science Daily
One option would be to introduce herbicide resistance genes into the de novo crop and then use herbicides to kill the weeds.
From Science Daily
Today, scientists use advanced technology to design new synthetic drug compounds with the right properties and characteristics, also known as "de novo drug design."
From Science Daily
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
