de novo

[ dee noh-voh, dey, dih; Latin de noh-woh ]
See synonyms for de novo on
  1. anew; afresh; again; from the beginning: We reviewed the court’s decision de novo during the rehearing.

  2. independently of external forces; from within; spontaneously:Mutations associated with autism often occur de novo rather than through inheritance.

  1. occurring or arising spontaneously or independently of external forces; spontaneous:de novo mutations;de novo synthesis of steroids from cholesterol.

  2. made from scratch rather than developed from or based on something preexisting, and hence new, novel, or of a new type:de novo protein design;de novo banks.

  1. De No·vo, noting or related to a type of FDA classification allowing novel medical devices with no precedent on the market to be sold:a De Novo request; De Novo classification.

Origin of de novo

First recorded in 1620–30; from Latin dē novō “anew, afresh, again”

Words Nearby de novo Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2024

How to use de novo in a sentence

  • As is well known, a language is not created de novo, but by a slow process of development.

    North America | Israel C. Russell
  • In the illustration above we have assumed that a monopoly was starting de novo.

    The Evolution of Modern Capitalism | John Atkinson Hobson

British Dictionary definitions for de novo

de novo

/ Latin (diː ˈnəʊvəʊ) /

  1. from the beginning; anew

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012