dedifferentiate

American

[dee-dif-uh-ren-shee-ayt] / ˌdi dɪf əˈrɛn ʃiˌeɪt /

verb (used without object)

Biology.

dedifferentiated, dedifferentiating

to undergo dedifferentiation.

Etymology

Origin of dedifferentiate

First recorded in 1915–20; back formation from dedifferentiation

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

dedifferentiate dedifferentiated

“The addition of vitamin D differentiates brain cells—be they glia, be they neurons—and will push them down various lineages. If there is an absence of this vitamin, you will dedifferentiate the brain,” Eyles says.

From Scientific American ● Mar. 13, 2023

Mrs. Coe-Jones was diagnosed in March with dedifferentiated chondrosarcoma, a type of bone cancer that forms in cartilage-producing cells.

From Washington Post ● Nov. 14, 2016

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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023