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Which character was the antagonist in the first Despicable Me movie?

despicable

American  
[des-pi-kuh-buhl, dih-spik-uh-] / ˈdɛs pɪ kə bəl, dɪˈspɪk ə- /

adjective

  1. An image of the word despicable as defined by deserving to be despised, or regarded with distaste, disgust, or disdain; contemptible.

    deserving to be despised, or regarded with distaste, disgust, or disdain; contemptible.

    He was a mean, despicable man, who treated his wife and children badly.

    Synonyms:
    detestable, mean, vile
    Antonyms:
    admirable

despicable British  
/ dɪˈspɪkəbəl, ˈdɛspɪk- /

adjective

  1. worthy of being despised; contemptible; mean

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of despicable

1545–55; < Late Latin dēspicābilis, equivalent to Latin dēspic ( ārī ) to despise or dēspic ( ere ) to look down ( dē- de- + -spic- look, combining form of specere ) + -ābilis -able

Explanation

Stealing the last piece of food from a starving child goes way beyond mean. It's despicable — a vile and harmful act. Mean, nasty, and scummy are synonyms of despicable, but they don't fully convey the awfulness of despicable. A man who lies to get a promotion meant for his co-worker would be considered mean. But the despicable man — the one who is so awful and worthless that he deserves to be despised — is the one who burns down the office building and frames his co-worker for it.

Keep Reading on Vocabulary.com

Vocabulary lists containing despicable

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Kim Yo Jong, the powerful sister of North Korea's leader, responded by calling Seoul "really despicable" on Friday and once again denied Pyongyang was behind the blasts.

From Barron's ● Oct. 3, 2026

In the first public response from Pyongyang, Kim Yo Jong, the sister of North Korean leader Kim Jong Un said South Korea "even called for an apology" and added it is "really despicable".

From Barron's ● Oct. 2, 2026

“This kind of despicable violence is not who we are as a city,” the mayor said on social media.

From The Wall Street Journal ● Jul. 24, 2026

The French Football Federation — which said in a statement that Amarilla’s remarks were “utterly despicable and unacceptable” and “criminal and reprehensible” — turned in a complaint to the national unit for combating online hate.

From Los Angeles Times ● Jul. 7, 2026

It fit me perfectly, sullied only by the despicable blue cockade I pinned to my breast.

From "The Detective's Assistant" by Kate Hannigan

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