differentiation

American  

[dif-uh-ren-shee-ey-shuhn] / ˌdɪf əˌrɛn ʃiˈeɪ ʃən /

noun

1. the act or process of differentiating, or the state of being differentiated.

2. Mathematics. the operation of finding the differential or derivative of a function.

3. Biology. the process by which cells or tissues change from relatively generalized to specialized kinds, during development.

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differentiation British  

/ ˌdɪfəˌrɛnʃɪˈeɪʃən /

noun

1. the act, process, or result of differentiating

2. maths an operation used in calculus in which the derivative of a function or variable is determined; the inverse of integration See integration

3. any process in which a mixture of materials separates out partially or completely into its constituent parts, as in the cooling and solidification of a magma into two or more different rock types or in the gradual separation of an originally homogeneous earth into crust, mantle, and core

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differentiation Scientific  

/ dĭf′ə-rĕn′shē-ā′shən /

1. In calculus, the process of computing the derivative of a function.

2. Compare integration

3. The process by which cells or parts of an organism change during development to serve a specific function. The cells of an animal in its early embryonic phase, for example, are identical at first but develop by differentiation into specific tissues, such as bone, heart muscle, and skin. The factors determining the differentiation of any particular cell are not well understood, but in deuterostomes (vertebrates and other complex animals) they include the location of the cell relative to other cells.

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Etymology

Origin of differentiation

First recorded in 1800–10; differentiat(e) + -ion

Explanation

Differentiation is how someone or something is set apart from others. If you make a differentiation between one brand of toothpaste and another, you point out how they're distinct. You can see the word different in differentiation. The -tion ending tips you off that differentiation is the noun form of different: differentiation refers to the differences themselves. Suppose two very similar movies come out at the same time. The studios will work to achieve differentiation in the films' trailers, with one highlighting the chemistry between the romantic leads and the other showing moments of slap-stick comedy.

Example Sentences

If competitive differentiation is the first thing investors look for when justifying such a high valuation, the second is a huge untapped market.

From Barron's • Apr. 30, 2026

The property was described as a shared residential and clinical space with "little to no differentiation between the two", which was "dirty and unhygienic".

From BBC • Apr. 28, 2026

According to the authors, only 1 to 4% of genetic differentiation among living human populations can be traced to variation between these ancestral stem populations.

From Science Daily • Apr. 26, 2026

Already, Harvard has pushed back the timeline for implementing a cap after students raised concerns in town hall discussions that exams don’t allow for enough differentiation, said Claybaugh.

From The Wall Street Journal • Apr. 3, 2026

This process, the first half of calculus, is now known as differentiation; however, Newton's method of differentiation doesn't look very much like the one we use today.

From "Zero: The Biography of a Dangerous Idea" by Charles Seife