differentiation

American  

[dif-uh-ren-shee-ey-shuhn] / ˌdɪf əˌrɛn ʃiˈeɪ ʃən /

noun

differentiations plural

1. the act or process of differentiating, or the state of being differentiated.

2. Mathematics. the operation of finding the differential or derivative of a function.

3. Biology. the process by which cells or tissues change from relatively generalized to specialized kinds, during development.

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differentiation British  

/ ˌdɪfəˌrɛnʃɪˈeɪʃən /

noun

1. the act, process, or result of differentiating

2. maths an operation used in calculus in which the derivative of a function or variable is determined; the inverse of integration See integration

3. any process in which a mixture of materials separates out partially or completely into its constituent parts, as in the cooling and solidification of a magma into two or more different rock types or in the gradual separation of an originally homogeneous earth into crust, mantle, and core

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differentiation Scientific  

/ dĭf′ə-rĕn′shē-ā′shən /

1. In calculus, the process of computing the derivative of a function.

2. Compare integration

3. The process by which cells or parts of an organism change during development to serve a specific function. The cells of an animal in its early embryonic phase, for example, are identical at first but develop by differentiation into specific tissues, such as bone, heart muscle, and skin. The factors determining the differentiation of any particular cell are not well understood, but in deuterostomes (vertebrates and other complex animals) they include the location of the cell relative to other cells.

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Other Word Forms

Noun Inflected Forms

• differentiations
  plural

Etymology

Origin of differentiation

First recorded in 1800–10; differentiat(e) + -ion

Explanation

Differentiation is how someone or something is set apart from others. If you make a differentiation between one brand of toothpaste and another, you point out how they're distinct. You can see the word different in differentiation. The -tion ending tips you off that differentiation is the noun form of different: differentiation refers to the differences themselves. Suppose two very similar movies come out at the same time. The studios will work to achieve differentiation in the films' trailers, with one highlighting the chemistry between the romantic leads and the other showing moments of slap-stick comedy.

Example Sentences

The reaction of the market to these announcements, however, showed little differentiation.

From MarketWatch • Jun. 11, 2026

It's useful to think about what will remain strong sources of differentiation: ownership of physical resources; large social networks; proprietary data; high customer switching costs; strong distribution channels; intellectual property; talent.

From The Wall Street Journal • Jun. 10, 2026

Traditionally, AI systems compute these derivatives using a process called recursive automatic differentiation.

From Science Daily • May 6, 2026

Meta isn’t helped by the fact that it doesn’t have a cloud business, either, and huge amounts begin raking in by its Mag Seven rivals suggest an even greater level of differentiation going forward.

From Barron's • Apr. 30, 2026

Newton’s method of differentiation was based on a notational trick: he let the fluxions change, but he only let them change infinitesimally.

From "Zero: The Biography of a Dangerous Idea" by Charles Seife