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difficile

American  
[dif-i-seel, dee-fee-seel] / ˌdɪf ɪˈsil, di fiˈsil /

adjective

  1. hard to deal with, satisfy, or please.

  2. hard to do; difficult.


Etymology

Origin of difficile

1470–80; < French < Latin difficilis difficult; dif-, facile

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

C. difficile is a stubborn intestinal bacterium that can cause serious illness, especially in older adults and people with weakened health.

From Science Daily

"With existing antibiotics, C. difficile sometimes reappears just weeks after treatment," says researcher and lead author Elma Mons.

From Science Daily

"Those bacteria actually protect against C. difficile," says Mons.

From Science Daily

These microbes help stop leftover spores from growing into harmful C. difficile bacteria and triggering another infection.

From Science Daily

Even at a low dose, the drug is powerful enough to effectively eliminate C. difficile.

From Science Daily