difficile

[dif-i-seel, dee-fee-seel]

adjective

1. hard to deal with, satisfy, or please.

2. hard to do; difficult.

Word History and Origins

Origin of difficile¹

1470–80; < French < Latin difficilis difficult; dif-, facile

Example Sentences

Faecal transplants – also known as a trans-poo-tion - are already approved for treating severe diarrhoea caused by Clostridium difficile bacteria.

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But scientists noticed hints that faecal transplants for C. difficile also seemed to get rid of superbugs.

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The researchers are currently working on modifying the system to help combat Clostridioides difficile, commonly referred to as C. diff, a bacterium that can cause diarrhea and colitis, among other symptoms.

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The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.

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FMT has a 90% cure rate for C. difficile infection.

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Related Words

• ambitious 
• arduous 
• burdensome 
• challenging 
• crucial 
• demanding 
• laborious 
• onerous 
• painful 
• problematic 
• severe 
• strenuous 
• tough 
• troublesome