difficile
Americanadjective
-
hard to deal with, satisfy, or please.
-
hard to do; difficult.
Etymology
Origin of difficile
1470–80; < French < Latin difficilis difficult; see dif-, facile
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
A team led by Prof. Rolf Müller, department head and scientific director at HIPS, has now identified a promising drug candidate that specifically targets C. difficile while preserving much of the gut's beneficial microbial community.
From Science Daily ● Oct. 20, 2026
Instead, most of it remained in the large intestine, where C. difficile infections occur.
From Science Daily ● Oct. 20, 2026
This disruption allows C. difficile to multiply rapidly, potentially causing severe intestinal inflammation that can become chronic.
From Science Daily ● Oct. 20, 2026
These microbes help stop leftover spores from growing into harmful C. difficile bacteria and triggering another infection.
From Science Daily ● Mar. 11, 2026
Within months, outbreaks of antibiotic-resistant Pseudomonas aeruginosa, Clostridium difficile, and E. coli are observed in patients around the world.
From "We Are the Ants" by Shaun David Hutchinson
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