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Synonyms

difficile

American  
[dif-i-seel, dee-fee-seel] / ˌdɪf ɪˈsil, di fiˈsil /

adjective

  1. hard to deal with, satisfy, or please.

  2. hard to do; difficult.


Etymology

Origin of difficile

1470–80; < French < Latin difficilis difficult; see dif-, facile

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

C. difficile is a stubborn intestinal bacterium that can cause serious illness, especially in older adults and people with weakened health.

From Science Daily • Mar. 11, 2026

But scientists noticed hints that faecal transplants for C. difficile also seemed to get rid of superbugs.

From BBC • Jun. 7, 2025

Faecal transplants – also known as a trans-poo-tion - are already approved for treating severe diarrhoea caused by Clostridium difficile bacteria.

From BBC • Jun. 7, 2025

FMT has a 90% cure rate for C. difficile infection.

From Salon • May 10, 2024

Excessive abdominal noise is an uncommon, but not unprecedented, presenting symptom of infection with the bacteria Clostridium difficile, which can be fatal.

From "Turtles All the Way Down" by John Green