digitoxin

American  

[dij-i-tok-sin] / ˌdɪdʒ ɪˈtɒk sɪn /

noun

Pharmacology.

1. a white, crystalline, water-insoluble cardiac glycoside, C 41 H 64 O 13 , or a mixture of cardiac glycosides of which this is the chief constituent, obtained from digitalis and used in the treatment of congestive heart failure.

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digitoxin British  

/ ˌdɪdʒɪˈtɒksɪn /

noun

1. a white toxic bitter-tasting glycoside, extracted from the leaves of the purple foxglove ( Digitalis purpurea ) and used in the treatment of heart failure and some abnormal heart rhythms. Formula: C 41 H 64 O 13

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digitoxin Scientific  

/ dĭj′ĭ-tŏk′sĭn /

1. A highly active glycoside derived from digitalis and prescribed in the treatment of certain cardiac conditions. Chemical formula: C ₄₁ H ₆₄ O ₁₃ .

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Etymology

Origin of digitoxin

First recorded in 1880–85; digi(talis) + toxin

Example Sentences

Foxglove - digitalis - is a source of digitoxin, a glycoside in the drug digitalis, which has been used as a heart stimulant since 1785.

From BBC • Jul. 10, 2023

But the heart stimulant digitoxin causes breaks, said Buffalo's Dr. Maimon M. Cohen.

From Time Magazine Archive

If a patient is on digitoxin, one of the digitalis products, and then uses barbiturates for a while, his heart-medicine dosage should be checked, and possibly adjusted, twice.

From Time Magazine Archive

The tincture contains a fair proportion of both digitalin and digitoxin.

From Encyclopaedia Britannica, 11th Edition, Volume 8, Slice 4 "Diameter" to "Dinarchus" by Various

And in its action on the heart the digitonin dilates the coronary arteries, according to Macht, while the digitoxin acts on the heart muscle.

From Arteriosclerosis and Hypertension: with Chapters on Blood Pressure, 3rd Edition. by Warfield, Louis Marshall