[ dih-zeez ]
See synonyms for: diseasediseaseddiseasesdiseasing on Thesaurus.com

  1. a disordered or incorrectly functioning organ, part, structure, or system of the body resulting from the effect of genetic or developmental errors, infection, poisons, nutritional deficiency or imbalance, toxicity, or unfavorable environmental factors; illness; sickness; ailment.

  2. any abnormal condition in a plant that interferes with its vital physiological processes, caused by pathogenic microorganisms, parasites, unfavorable environmental, genetic, or nutritional factors, etc.

  1. any harmful, depraved, or morbid condition, as of the mind or society: His fascination with executions is a disease.

  2. decomposition of a material under special circumstances: tin disease.

verb (used with object),dis·eased, dis·eas·ing.
  1. to affect with disease; make ill.

Origin of disease

First recorded in 1300–50; Middle English disese, from Anglo-French dese(a)se, disaise; dis-1 + ease

Other words for disease

Opposites for disease

Other words from disease

  • dis·eas·ed·ly, adverb
  • dis·eas·ed·ness, noun

Words Nearby disease

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use disease in a sentence

British Dictionary definitions for disease


/ (dɪˈziːz) /

  1. any impairment of normal physiological function affecting all or part of an organism, esp a specific pathological change caused by infection, stress, etc, producing characteristic symptoms; illness or sickness in general

  2. a corresponding condition in plants

  1. any situation or condition likened to this: the disease of materialism

Origin of disease

C14: from Old French desaise; see dis- 1, ease

Other words from disease

  • Related adjective: pathological

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012