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dopamine

American  
[doh-puh-meen] / ˈdoʊ pəˌmin /

noun

dopamines plural
  1. Biochemistry. a catecholamine neurotransmitter in the central nervous system, retina, and sympathetic ganglia, acting within the brain to help regulate movement and emotion: its depletion may cause Parkinson's disease.

  2. Pharmacology. a dopamine preparation used to increase the force of contraction of the heart in the treatment of shock.


dopamine British  
/ ˈdɒpəmɪn /

noun

  1. a chemical found in the brain that acts as a neurotransmitter and is an intermediate compound in the synthesis of noradrenaline. Formula: (HO) 2 C 6 H 3 (CH 2 ) 2 NH 2

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Noun Inflected Forms

Etymology

Origin of dopamine

First recorded in 1955–60; see origin at dopa, amine

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Most current antidepressants work by targeting brain chemicals such as serotonin, dopamine, and norepinephrine.

From Science Daily • May 28, 2026

Sally's story is among the hundreds the BBC has heard over the past year and a half, describing the devastating side effects of dopamine agonist drugs.

From BBC • May 1, 2026

“You can get that dopamine hit so much quicker and so much more often,” said Fields, who specializes in addiction psychology and biology.

From MarketWatch • Apr. 17, 2026

An older sister turns to sewing her bin of fabric scraps into a quilt top or putting together a jigsaw puzzle to get her dopamine.

From The Wall Street Journal • Apr. 12, 2026

And each time you respond, you get a hit of dopamine.

From "A Deadly Wandering: A Mystery, a Landmark Investigation, and the Astonishing Science of Attention in the Digital Age" by Matt Richtel

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