dornase alfa

[ dawr-neys al-fuh, -neyz ]
/ ˈdɔr neɪs ˈæl fə, -neɪz /

a genetically engineered form of recombinant human DNase that reduces the viscosity of mucus in the lungs, especially in the treatment of cystic fibrosis.

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Also called rhDNase.

Origin of dornase alfa

First recorded in 1980–85; shortening and alteration of (recombinant human) d(e)o(xy)r(ibo)n(ucle)ase (1) + alpha
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2020

Medical definitions for dornase alfa

dornase alfa
[ dôrnās′ ălfə, -nāz′ ]

n.

A genetically engineered enzyme used to hydrolyze the DNA in bronchial mucus, facilitating its expectoration, in the treatment of cystic fibrosis.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.