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double-blind

American  
[duhb-uhl-blahynd] / ˈdʌb əlˈblaɪnd /

adjective

  1. of or relating to an experiment or clinical trial in which neither the subjects nor the researchers know which subjects are receiving the active medication, treatment, etc., and which are not: a technique for eliminating subjective bias from the test results.


double-blind British  

adjective

  1. of or relating to an experiment to discover reactions to certain commodities, drugs, etc, in which neither the experimenters nor the subjects know the particulars of the test items during the experiments Compare single-blind

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of double-blind

First recorded in 1935–40

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Dr. Prasad demanded that they conduct nothing less than double-blind randomized controlled trials in diseases for which such trials would be unethical or next to impossible because of their rarity.

From The Wall Street Journal • May 5, 2026

Dr. Sullivan will present the findings from the study, "Duodenal mucosal resurfacing prevents weight regain after tirzepatide withdrawal: REMAIN-1 multicenter, randomized, double-blind, sham-controlled clinical trial -- midpoint cohort results," abstract 642, at 8:30 a.m.

From Science Daily • Apr. 23, 2026

In minutes from the FDA’s Type A meeting—a meeting to discuss stalled development programs—the agency recommended uniQure conduct a further randomized, double-blind, sham surgery-controlled study, the company said.

From Barron's • Mar. 2, 2026

Today double-blind placebo-controlled trials are the gold standard in the FDA approval process: Participants are given either a drug or something that looks like one.

From Slate • Jan. 30, 2026

The trial is a double-blind study, so no one knows who is on the drug and who is taking the placebo, with researchers monitoring changes in iron levels in all participants.

From BBC • Feb. 11, 2025

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