doxepin

[dok-suh-pin]

noun

Pharmacology.

1. a tricyclic antidepressant, C 19 H 21 NO, used primarily to treat depression or anxiety.

Word History and Origins

Origin of doxepin¹

A contraction of the chemical name

Example Sentences

A different antihistamine compound has been developed specifically for sleep troubles — the prescription drug Silenor contains a low dose of doxepin.

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Antidepressants such as amitriptyline and doxepin also have been prescribed off-label for nerve pain.

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Tricyclic drugs including clomipramine, nortriptyline and doxepin were effective in the lab against types of brain, blood and skin cancers, Prof Pilkington says.

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One well-travelled path involves histamine blockers, such as doxepin, which has been used for decades as an antidepressant in doses of up to 150 milligrams.

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The depth of ligand penetration into the TM bundle is the deepest for doxepin in the histamine H1 receptor and shallowest for caffeine in A2AR.

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