doxorubicin

American  

[dok-suh-roo-buh-sin] / ˌdɒk səˈru bə sɪn /

noun

Pharmacology.

1. a cytotoxic antibiotic, C 27 H 29 NO 11 , derived from a variety of the bacterium Streptomyces peucetius and used in the treatment of sarcoma, malignant lymphoma, acute leukemia, and other cancers: administered intravenously, it is noted for its bright red color and potentially dangerous side effects.

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Etymology

Origin of doxorubicin

First recorded in 1970–75; d(e)ox(y)- + -o- + Latin rub(er) “red” (alluding to its color; rubric, red ¹ ) + -i- + -(my)cin

Example Sentences

When researchers created cancer cells that no longer responded to doxorubicin, the SFRP2 antibody still caused substantial cancer cell death.

From Science Daily

Published in the journal Cardiovascular Research, the WSU study focused on doxorubicin, a chemotherapy drug used to treat breast cancer, lymphoma, leukemia and other cancers.

From Science Daily

"What we're trying to do is to develop a method to locally deliver doxorubicin but also mitigate acidosis at the same time," Ahmed said.

From Science Daily

In the new work, the Leiden team tested two anthracycline variants that remove histones without breaking DNA: an approved cancer drug called aclarubicin, and a tweaked version of doxorubicin they call diMe-Doxo.

From Science Magazine

Treatment with exosome-encased doxorubicin also shrank the tumours to a greater degree than did doxorubicin alone.

From Nature