drug

¹ American  

[druhg] / drʌg /

noun

1. Pharmacology. a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well-being.

2. (in federal law)

   1. any substance recognized in the official pharmacopoeia or formulary of the nation.

   2. any substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in humans or other animals.

   3. any article, other than food, intended to affect the structure or any function of the body of humans or other animals.

   4. any substance intended for use as a component of such a drug, but not a device or a part of a device.

3. a habit-forming medicinal or illicit substance, especially a narcotic.

4. drugs,

   1. chemical substances prepared and sold as pharmaceutical items, either by prescription or over the counter.

   2. personal hygienic items sold in a drugstore, as toothpaste, mouthwash, etc.

5. Obsolete. any ingredient used in chemistry, pharmacy, dyeing, or the like.

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verb (used with object)

drugged, drugging

1. to administer a medicinal drug to.

2. to stupefy or poison with a drug.

3. to mix (food or drink) with a drug, especially a stupefying, narcotic, or poisonous drug.

4. to administer anything nauseous to.

verb phrase

1. drug up to take a drug, especially an illegal drug: athletes who drug up in the off-season.

   kids hiding under the school bleachers to drug up;

   athletes who drug up in the off-season.

idioms

1. drug on the market, a commodity that is overabundant or in excess of demand in the market. Also drug in the market.

drug ² American  

[druhg] / drʌg /

verb

Nonstandard: Chiefly Midland and Southern U.S.

1. a simple past tense and past participle of drag.

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Drug ³ American  

[droog] / drʊg /

noun

Zoroastrianism.

1. the cosmic principle of disorder and falsehood.

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drug British  

/ drʌɡ /

noun

1. any synthetic, semisynthetic, or natural chemical substance used in the treatment, prevention, or diagnosis of disease, or for other medical reasons

2. a chemical substance, esp a narcotic, taken for the pleasant effects it produces

3. a commodity available in excess of the demands of the market

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verb

1. to mix a drug with (food, drink, etc)

2. to administer a drug to

3. to stupefy or poison with or as if with a drug

drug Scientific  

/ drŭg /

1. A chemical substance, especially one prescribed by a medical provider, that is used in the diagnosis, treatment, or prevention of a condition or disease. Drugs are prescribed for a limited amount of time, as for an acute infection, or on a regular basis for chronic disorders, such as hypertension.

2. A chemical substance such as a narcotic or a hallucinogen that affects the central nervous system and is used recreationally for perceived desirable effects on personality, perception, or behavior. Many recreational drugs are used illicitly and can be addictive.

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Other Word Forms

• druggy adjective

Etymology

Origin of drug¹

First recorded in 1300–50; Middle English drogges (plural), from Middle French drogue, of obscure origin

Origin of Drug³

From the Avestan word drauga

Example Sentences

Stephen Ubl, president of the drug industry trade group Pharmaceutical Research and Manufacturers of America, said: “Tariffs on cutting-edge medicines will increase costs and could jeopardize billions in U.S. investments announced in the last year.”

From The Wall Street Journal • Apr. 2, 2026

The Wegovy pill has had one of the best drug launches in history.

From The Wall Street Journal • Apr. 1, 2026

It’s a big step, seeing as both companies have explored more efficient methods of drug delivery in a bid to differentiate themselves.

From Barron's • Apr. 1, 2026

The team believes this discovery could influence multiple fields, including cancer research, drug delivery, tissue repair and synthetic biology.

From Science Daily • Apr. 1, 2026

This would guarantee sales for the drug companies and motivate them to produce the drugs at cheap prices.

From "Mountains Beyond Mountains" by Tracy Kidder and Michael French

Related Words

• cure
• medicine
• narcotic
• pharmaceutical
• pill
• poison
• prescription
• remedy
• stimulant