dysregulation
noun
a disruption in a physical or psychological system's ability to adapt or respond appropriately to stimuli.
The grammatical form denoting more than one person, place, thing, or idea.
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This occurs via inflammatory processes in the brain-gut microbiome system involved in dysregulations of glutamatergic signaling and modulation of the frontal-striatal circuits.
From Science Daily ● Oct. 2, 2023