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Synonyms

efficacy

American  
[ef-i-kuh-see] / ˈɛf ɪ kə si /
Sometimes efficacity

noun

efficacies plural
  1. the capacity for producing a desired result or effect.

    Short, frequent periods of practice were shown to have greater efficacy than longer and less frequent ones.

  2. a measure of the success of a vaccine or other pharmaceutical when used in the controlled environment of a clinical trial, as opposed to in the real world.


efficacy British  
/ ˈɛfɪkəsɪ /

noun

  1. the quality of being successful in producing an intended result; effectiveness

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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Derived Forms

Inflected Forms

Nouns

Etymology

Origin of efficacy

First recorded in 1520–30; from Latin efficācia, from efficāc- (stem of efficāx ) “effective, effectual” + -ia, noun suffix; see efficacious ( def. ), -y 3 ( def. )

Explanation

The degree to which a method or medicine brings about a specific result is its efficacy. You might not like to eat it, but you can't question the efficacy of broccoli as a health benefit. Efficacy is a more formal way to say effectiveness, both of which stem from the Latin verb efficere "to work out, accomplish." The effectiveness, or efficacy, of something is how well it works or brings the results you hoped for. A scientist does research to determine the efficacy of a vaccine or medicine under development. If it is efficacious, it will cure or prevent a disease.

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Vocabulary lists containing efficacy

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

This allows for dose customization but isn’t subject to the same reviews for safety, efficacy or consistency, and may carry added risks related to quality control, potency variation or contamination.

From Los Angeles Times • Jun. 23, 2026

And while experts don’t think A.I. will crack this one any time soon, they do expect that the efficacy of these A.I. carpet-bombing campaigns will increase as the technology continues to improve.

From Slate • Jun. 22, 2026

"Despite these promising results, we're continuing to move forward with new studies to more thoroughly evaluate the efficacy and safety of the system," she adds.

From Science Daily • Jun. 19, 2026

Put aside arguments on the reasoning and efficacy of the medical and scientific regime.

From The Wall Street Journal • Jun. 18, 2026

This discipline is of such efficacy that not only does it maintain those who were born princes, but it enables men of private station on many occasions to rise to that position.

From "The Prince" by Niccolò Machiavelli

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