[verb ih-noo-klee-eyt, ih-nyoo-; adjective ih-noo-klee-it, -eyt, ih-nyoo-]
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verb (used with object), e·nu·cle·at·ed, e·nu·cle·at·ing.
  1. Biology. to deprive of the nucleus.
  2. to remove (a kernel, tumor, eyeball, etc.) from its enveloping cover.
  3. Archaic. to bring out; disclose; explain.
  1. having no nucleus.

Origin of enucleate

1540–50; < Latin ēnucleātus (past participle of ēnucleāre to remove the pit from (fruit)), equivalent to ē- e-1 + nucle(us) nucleus + -ātus -ate1
Related formse·nu·cle·a·tion, noun
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

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British Dictionary definitions for enucleate


verb (ɪˈnjuːklɪˌeɪt) (tr)
  1. biology to remove the nucleus from (a cell)
  2. surgery to remove (a tumour or other structure) from its capsule without rupturing it
  3. archaic to explain or disclose
adjective (ɪˈnjuːklɪɪt, -ˌeɪt)
  1. (of cells) deprived of their nuclei
Derived Formsenucleation, noun

Word Origin for enucleate

C16: from Latin ēnūcleāre to remove the kernel, from nūcleus kernel
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

enucleate in Medicine


  1. To remove something, such as a tumor or an eye, whole and without rupture from an enveloping cover or sac.
  2. To remove the nucleus of a cell.
  1. Lacking a nucleus.
Related formse•nu′cle•ation n.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.