epiblast

[ep-uh-blast]

noun

Embryology.

1. the primordial outer layer of a young embryo before the segregation of the germ layers, capable of becoming the ectoderm and containing cells capable of becoming the mesoderm and endoderm.

epiblast

/ ˈɛpɪˌblæst /

noun

1. Also called: ectoblast. embryol the outermost layer of an embryo, which becomes the ectoderm at gastrulation

Other Word Forms

• epiblastic adjective

Word History and Origins

Origin of epiblast¹

First recorded in 1865–70; epi- + -blast

Example Sentences

At this point, the head develops from the inner cell layer of the cup, the epiblast, and the tail develops on the opposite side.

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The epiblast emits Nodal, while the lid, the extraembryonic endoderm, releases the counterpart BMP.

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To this end, they developed a novel embryo-like model system consisting of a layer of epiblast and a layer of VE cells -- a cup without a lid.

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"We were then able to see epiblast symmetry breaking, marked by BRA expression, for the first time with the high molecular resolution," says Riccardo De Santis, a research associate in the Brivanlou lab and lead author on the study.

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With this unprecedented clarity, the team directly observed two key moments in gastrulation: the first epiblast symmetry-breaking event and the emergence of the molecular markers of the primitive streak and mesoderm upon in vitro attachment.

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