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factor VIII

American  
factor VIII British  

noun

  1. a protein that participates in the clotting of blood. It is extracted from donated serum and used in the treatment of the commonest type of haemophilia, in which it is absent

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of factor VIII

First recorded in 1960–65

Example Sentences

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See Examples For:

Mr Evans' father was among thousands of people to be infected by contaminated blood in the 1970s and '80s after being given a blood clotting agent called factor VIII.

From BBC Feb. 3, 2023

Only 15% of people with haemophilia have haemophilia B. Most have haemophilia A—a genetic disorder caused by a deficiency in a different blood-clotting protein called factor VIII, which is encoded by a different gene.

From Scientific American Dec. 9, 2022

They cannot carry a large gene, and the gene for factor VIII, needed to treat hemophilia A, is enormous.

From New York Times Aug. 13, 2018

The bispecific antibody has a half-life of about 30 days, much longer than the 12-hour upper limit of factor VIII, Shima says.

From Nature Nov. 25, 2014

The two main forms of the disease are hemophilia A, caused by a lack of clotting factor VIII, and hemophilia B, caused by a lack of clotting factor IX.

From Reuters Dec. 11, 2011

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