factor VIII

noun

1. antihemophilic factor.

factor VIII

noun

1. a protein that participates in the clotting of blood. It is extracted from donated serum and used in the treatment of the commonest type of haemophilia, in which it is absent

Word History and Origins

Origin of factor VIII¹

First recorded in 1960–65

Example Sentences

Mr Evans' father was among thousands of people to be infected by contaminated blood in the 1970s and '80s after being given a blood clotting agent called factor VIII.

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Only 15% of people with haemophilia have haemophilia B. Most have haemophilia A—a genetic disorder caused by a deficiency in a different blood-clotting protein called factor VIII, which is encoded by a different gene.

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By the mid 1970s, a new treatment for haemophilia, known as factor VIII/IX, became available for the first time.

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Each patient was given a single injection of recombinant factor VIII, followed by a washout period of at least 3 days before an injection of the fusion protein BIVV001.

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Those with the condition are either missing or low on a clotting protein called factor VIII, or FVIII.

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