fibrosis

[fahy-broh-sis]

noun

Pathology.

1. the development in an organ of excess fibrous connective tissue.

fibrosis

/ faɪˈbrəʊsɪs, faɪˈbrɒtɪk /

noun

1. the formation of an abnormal amount of fibrous tissue in an organ or part as the result of inflammation, irritation, or healing

Other Word Forms

• fibrotic adjective

Word History and Origins

Origin of fibrosis¹

First recorded in 1870–75; fibr- + -osis

Example Sentences

The gene treatment also reduced heart tissue damage, known as fibrosis, and lowered the number of "aged" cells in the heart.

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Some inherited diseases, including cystic fibrosis, hemophilia, and Tay Sachs disease, involve multiple genetic mutations within a person's DNA.

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Drugs that fine-tune C/EBPα activity, for example, could help AT2 cells rebuild lung tissue more effectively or reduce scarring in conditions like pulmonary fibrosis.

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In any case, the results raise new questions, such as whether the drugs will be equally effective in more advanced stages of the disease, when fibrosis is present.

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We expect the company’s launch of Alyftrek in cystic fibrosis will do well over time.

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