folinic acid

American

[foh-lin-ik] / foʊˈlɪn ɪk /

noun

Biochemistry, Pharmacology.

a crystalline, slightly water-soluble solid, C 20 H 23 N 7 O 7 , produced by fermentation or derived from folic acid, used in medicine in the treatment of certain anemias.

Etymology

Origin of folinic acid

First recorded in 1945–50; fol(ic) + -in ² + -ic

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Leucovorin is a form of vitamin B-9 referred to as folinic acid.

From The Wall Street Journal • Mar. 10, 2026

The charity says the suggestion that folate may improve some symptoms comes from trials of a cancer drug known as leucovorin or folinic acid.

From BBC • Sep. 23, 2025

Also known as folinic acid, leucovorin is a form of the B vitamin folate.

From Los Angeles Times • Sep. 22, 2025

She was advised to immediately stop taking methotrexate and Enbrel and begin high doses of folinic acid, which counters the effects of methotrexate.

From Washington Post • May 14, 2022

The drug Dr. Sullivan and his colleagues chose was Methotrexate, because it has a handy, harmless and effective antagonist in folinic acid, also known as CF, for citrovorum factor.

From Time Magazine Archive

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023