Dictionary.com
Thesaurus.com

fuck up

British  

verb

  1. to damage or bungle

    to fuck up a machine

  2. to make confused

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. an act or an instance of bungling

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
fuck up Idioms  
  1. Ruin, botch, spoil. For example, Don't tell me you're going to fuck up again . It is also put as be fucked up , meaning “be ruined or spoiled,” as in This entire project is fucked up . This vulgar usage dates from the early 1900s but did not become widespread until about 1940.

  2. Act carelessly or foolishly, mess up, as in I'm sorry, I really fucked up when I invited them . [ Vulgar slang ; c. 1940]

  3. Break down, fail, as in If the flash mechanism fucks up again, I won't get a picture . [ Vulgar slang ; c. 1980]

  4. be fucked up . Be very confused or mentally ill; also, intoxicated. For example, He was so fucked up they had to hospitalize him , or What a party—I sure got fucked up . [ Vulgar slang ; 1940s]