embitter
verb (used with object)
to make bitter; cause to feel bitterness.
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
She will be rid of this hateful entanglement that has been embittering her life for months, and—and, of course, he won't keep her to this absurd arrangement after a while.
From Portia or By Passions Rocked by Duchess