Huntington's disease

American  

[huhn-ting-tuhnz di-zeez] / ˈhʌn tɪŋ tənz dɪˌziz /

noun

Pathology.

1. a hereditary disease of the central nervous system characterized by brain deterioration resulting in involuntary movement and unsteady gait, cognitive impairment and memory decline, and depression or other alterations in mood, with symptoms usually appearing in the fourth decade of life. HD

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Huntington's disease British  

/ ˈhʌntɪŋtən /

noun

1. Former name: Huntington's chorea.  a rare hereditary type of chorea, marked by involuntary jerky movements, impaired speech, and increasing dementia

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Etymology

Origin of Huntington's disease

Named after George S. Huntington (1850–1916), U.S. physician, who described it in 1872

Example Sentences

Prasad had reportedly been involved in the decision to request a new trial for uniQure’s experimental gene therapy for Huntington’s disease.

From MarketWatch • Mar. 9, 2026

Federal health officials, facing criticism from lawmakers for recent rejections of rare-disease drugs, attacked an Amsterdam-based biotech company seeking approval of a Huntington’s disease treatment and accused it of lying.

From The Wall Street Journal • Mar. 5, 2026

The FDA said the biotech company’s trial data failed to demonstrate the effectiveness of its investigational Huntington’s disease therapy.

From Barron's • Mar. 2, 2026

Neurodegenerative disorders such as Alzheimer's, Parkinson's, and Huntington's disease occur when neurons gradually deteriorate and die.

From Science Daily • Oct. 14, 2025

Within two years, HIV, cerebral palsy, Huntington's disease, blindness, polio, and male pattern baldness are eradicated.

From "We Are the Ants" by Shaun David Hutchinson