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Huntington's disease

American  
[huhn-ting-tuhnz di-zeez] / ˈhʌn tɪŋ tənz dɪˌziz /

noun

Pathology.
  1. a hereditary disease of the central nervous system characterized by brain deterioration resulting in involuntary movement and unsteady gait, cognitive impairment and memory decline, and depression or other alterations in mood, with symptoms usually appearing in the fourth decade of life. HD


Huntington's disease British  
/ ˈhʌntɪŋtən /

noun

  1. Former name: Huntington's chorea.  a rare hereditary type of chorea, marked by involuntary jerky movements, impaired speech, and increasing dementia

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of Huntington's disease

Named after George S. Huntington (1850–1916), U.S. physician, who described it in 1872

Example Sentences

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See Examples For:

Earlier this month, uniQure said the FDA had reversed course on its Huntington’s disease gene therapy, clearing a path to file for accelerated approval after previously requesting a new trial.

From The Wall Street Journal Jun. 22, 2026

No vitamin K derived drug has yet been shown to repair the brains of people with Alzheimer's, Parkinson's, or Huntington's disease.

From Science Daily May 27, 2026

Prasad had reportedly been involved in the decision to request a new trial for uniQure’s experimental gene therapy for Huntington’s disease.

From MarketWatch Mar. 9, 2026

This is the second time Dr. Prasad is being pushed out of the agency, and to understand why, see his handling of UniQure’s gene therapy for Huntington’s disease.

From The Wall Street Journal Mar. 7, 2026

Within two years, HIV, cerebral palsy, Huntington's disease, blindness, polio, and male pattern baldness are eradicated.

From "We Are the Ants" by Shaun David Hutchinson

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