hydrochloride

American  

[hahy-druh-klawr-ahyd, -id, -klohr-] / ˌhaɪ drəˈklɔr aɪd, -ɪd, -ˈkloʊr- /

noun

1. a salt, especially of an alkaloid, formed by the direct union of hydrochloric acid with an organic base that makes the organic constituent more soluble.

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hydrochloride British  

/ ˌhaɪdrəˈklɔːraɪd /

noun

1. a quaternary salt formed by the addition of hydrochloric acid to an organic base, such as aniline hydrochloride, [C 6 H 5 NH 3 ] ⁺ Cl ^-

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hydrochloride Scientific  

/ hī′drə-klôr′īd′ /

1. A salt containing the group HCl. Many important drugs are hydrochlorides.

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Etymology

Origin of hydrochloride

First recorded in 1820–30; hydro- ² + chloride

Example Sentences

It suggests one of the first medications people should be offered is Xonvea, scientifically known as doxylamine succinate and pyridoxine hydrochloride.

From BBC • Dec. 10, 2025

Beta blockers such as propranolol hydrochloride have been approved by the Food and Drug Administration for chest pain, migraine prevention, involuntary tremors, abnormal heart rhythms and other uses.

From New York Times • Apr. 3, 2024

Next, they treated the cloth with hydroxylamine hydrochloride to add amidoxime groups to the polymers.

From Science Daily • Dec. 13, 2023

If hydrocortisone doesn’t help, Butler suggests trying an anti-itch cream with pramoxine hydrochloride.

From Washington Post • Feb. 13, 2023

Aniline, 13, 182, 184, 185, 186, 188. — black, 79, 205, 234. — grey B, 229, 231. — hydrochloride, 181. — oil, 206, 207. — salt, 207.

From The Dyeing of Cotton Fabrics A Practical Handbook for the Dyer and Student by Beech, Franklin