Dictionary.com
Thesaurus.com

hydrochloride

American  
[hahy-druh-klawr-ahyd, -id, -klohr-] / ˌhaɪ drəˈklɔr aɪd, -ɪd, -ˈkloʊr- /

noun

  1. a salt, especially of an alkaloid, formed by the direct union of hydrochloric acid with an organic base that makes the organic constituent more soluble.


hydrochloride British  
/ ˌhaɪdrəˈklɔːraɪd /

noun

  1. a quaternary salt formed by the addition of hydrochloric acid to an organic base, such as aniline hydrochloride, [C 6 H 5 NH 3 ] + Cl -

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

hydrochloride Scientific  
/ hī′drə-klôrīd′ /
  1. A salt containing the group HCl. Many important drugs are hydrochlorides.


Etymology

Origin of hydrochloride

First recorded in 1820–30; hydro- 2 + chloride

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

It suggests one of the first medications people should be offered is Xonvea, scientifically known as doxylamine succinate and pyridoxine hydrochloride.

From BBC • Dec. 10, 2025

Next, they treated the cloth with hydroxylamine hydrochloride to add amidoxime groups to the polymers.

From Science Daily • Dec. 13, 2023

She gave me prescriptions for estradiol vaginal tablets, lidocaine hydrochloride jelly USP 2%, and OTC hyaluronic acid vaginal moisturizer.

From New York Times • Jan. 31, 2018

Naloxone hydrochloride, approved by the Food and Drug Administration in 1971, has long been carried by rescue personnel and used in emergency rooms.

From Washington Post • Nov. 22, 2015

An example of this important process is that of nitrous acid on aniline hydrochloride shown in the following equation:— C6H5NH2 + HCl + HNO2 2H2O + C6H5N:NCl Hydrochloric acid Nitrous Water, Diazo-benzene aniline, acid, chloride.

From The Dyeing of Cotton Fabrics A Practical Handbook for the Dyer and Student by Beech, Franklin

Vocabulary.com logo
by dictionary.com

Look it up. Learn it forever.

Remember "hydrochloride" for good with VocabTrainer. Expand your vocabulary effortlessly with personalized learning tools that adapt to your goals.

Take me to Vocabulary.com