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hydrochloride

American  
[hahy-druh-klawr-ahyd, -id, -klohr-] / ˌhaɪ drəˈklɔr aɪd, -ɪd, -ˈkloʊr- /

noun

  1. a salt, especially of an alkaloid, formed by the direct union of hydrochloric acid with an organic base that makes the organic constituent more soluble.


hydrochloride British  
/ ˌhaɪdrəˈklɔːraɪd /

noun

  1. a quaternary salt formed by the addition of hydrochloric acid to an organic base, such as aniline hydrochloride, [C 6 H 5 NH 3 ] + Cl -

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

hydrochloride Scientific  
/ hī′drə-klôr′īd′ /
  1. A salt containing the group HCl. Many important drugs are hydrochlorides.


Etymology

Origin of hydrochloride

First recorded in 1820–30; hydro- 2 + chloride


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

It suggests one of the first medications people should be offered is Xonvea, scientifically known as doxylamine succinate and pyridoxine hydrochloride.

From BBC ● Dec. 10, 2025

Next, they treated the cloth with hydroxylamine hydrochloride to add amidoxime groups to the polymers.

From Science Daily ● Dec. 13, 2023

If hydrocortisone doesn’t help, Butler suggests trying an anti-itch cream with pramoxine hydrochloride.

From Washington Post ● Feb. 13, 2023

Decades in the development, fluoxetine hydrochloride was first introduced to the market as an antidepressant in 1987.

From Salon ● Jan. 8, 2020

About a hundred grammes of hydroxylamine hydrochloride, NH2OH.HCl, were dissolved in six hundred cubic centimeters of warm methyl alcohol.

From Scientific American Supplement, No. 841, February 13, 1892 by Various

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