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hydrophobic

American  
[hahy-druh-foh-bik] / ˌhaɪ drəˈfoʊ bɪk /

adjective

  1. of or relating to hydrophobia.

  2. Chemistry. having little or no affinity for water.


hydrophobic British  
/ ˌhaɪdrəˈfəʊbɪk /

adjective

  1. of or relating to hydrophobia

  2. chem tending not to dissolve in, mix with, or be wetted by water Compare hydrophilic

    a hydrophobic colloid

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms


Etymology

Origin of hydrophobic

First recorded in 1640–50; hydrophobe + -ic


Vocabulary lists containing hydrophobic

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The platform can also be adapted to carry other hydrophobic disease-modifying compounds.

From Science Daily ● Aug. 31, 2026

Such fabrics are hydrophobic, or water hating, similar to grease and oils.

From The Wall Street Journal ● Jun. 22, 2026

By analyzing the protonation/deprotonation of glycine molecules, the researchers observed a hydrophobic water/water interface close to the metal surface, leading to a destabilization of zwitterionic forms of glycine.

From Science Daily ● Apr. 11, 2024

This can be covalent bonds, hydrogen bridge bonds, van der Waals forces, and hydrophobic interactions.

From Science Daily ● Apr. 4, 2024

He was extremely fond of his glass of wine, and had, beside, that hydrophobic distaste, which has been imagined essential to the true poet.

From The American Quarterly Review, No. 17, March 1831 by Robert Walsh

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