hydroxylase

American  

[hahy-drok-suh-leys, -leyz] / haɪˈdrɒk səˌleɪs, -ˌleɪz /

noun

Biochemistry.

1. any enzyme that catalyzes the introduction of a hydroxyl group into a substance.

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Etymology

Origin of hydroxylase

First recorded in 1950–55; hydroxyl + -ase

Example Sentences

Willing, J., Cortes, L. R., Brodsky, J. M., Kim, T. & Juraska, J. M. Innervation of the medial prefrontal cortex by tyrosine hydroxylase immunoreactive fibers during adolescence in male and female rats.

From Nature • Feb. 20, 2018

Chemistry beet One key sticking point has been to identify an enzyme, a tyrosine hydroxylase, that would work in yeast to selectively convert tyrosine to L-DOPA, a key step along the pathway.

From Scientific American • May 19, 2015

The group tested an enzyme from sugar beets called a tyrosine hydroxylase.

From Science Magazine • May 18, 2015

People afflicted with PKU lack sufficient activity of the enzyme phenylalanine hydroxylase and are therefore unable to break down phenylalanine into tyrosine adequately.

From Textbooks • Jun. 19, 2013

Another private U.S. company, Akebia Therapeutics, also has a similar HIF-prolyl hydroxylase inhibitor in Phase II tests.

From Reuters • Apr. 19, 2013