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hypothesize

American  
[hahy-poth-uh-sahyz, hi-] / haɪˈpɒθ əˌsaɪz, hɪ- /
especially British, hypothesise

verb (used with object)

  • hypothesizes,
    present (3rd person singular)
  • hypothesized,
    past participle,  past
  • hypothesizing
    present participle
  1. to assume tentatively or set forth as a plausible explanation or as a reasonable basis for further investigation in the light of established facts.

    Given these data, we can hypothesize that the rise in truck accidents is directly related to the stressful work environment and unsafe driving practices of drivers.

  2. to theorize, infer, or tentatively conclude.

    He said little, but based on his body language and tone, I hypothesized that he had feelings for her.


verb (used without object)

  • hypothesizes,
    present (3rd person singular)
  • hypothesized,
    past participle,  past
  • hypothesizing
    present participle
  1. to form or set forth, based on established facts, a plausible explanation or reasonable basis for further investigation of something.

    She has written several well-researched papers hypothesizing about the origins of language.

  2. to theorize or draw tentative conclusions or inferences.

    I like to hypothesize about life in the next century.

hypothesize British  
/ haɪˈpɒθɪˌsaɪz /

verb

  1. to form or assume as a hypothesis

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

hypothesize Scientific  
/ hī-pŏth′ĭ-sīz′ /
  1. To form a hypothesis.


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Etymology

Origin of hypothesize

First recorded in 1730–40; hypothes(is) + -ize

Explanation

To hypothesize means simply to make a hypothesis. Which is just a scientific way of saying "make a really good educated guess." Ok, so when someone hypothesizes there's a little bit more involved than just guesswork. It involves using your past knowledge and available facts to try and predict what might happen. Scientists hypothesize all the time — it's the basis for every experiment. For example, doctors examining a werewolf might hypothesize that his furry face and oddball behavior stem from an illness and not the full moon.

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Vocabulary lists containing hypothesize

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

With fewer fat cells available, the researchers hypothesize that fat may accumulate more slowly after weight loss.

From Science Daily ● Oct. 11, 2026

The researchers hypothesize that the agents were using the tool to get around restrictions on their web browsing, for instance to access websites that have blocks against automated access.

From The Wall Street Journal ● Sep. 24, 2026

"A lot of people hypothesize what they would have done, or whether they would have been able to take on the attacker," said Astrid.

From BBC ● Nov. 6, 2025

“I would hypothesize that we didn’t have as many people in the office five days a week, even pre-COVID, just because of the nature of the work that takes place in Los Angeles.”

From Los Angeles Times ● Aug. 27, 2025

One can hypothesize that smell is produced by particles entering the nose.

From "The Invention of Science" by David Wootton

Emily Choquette, director of the Torrance-based Float Clinic and Research Center, says she hypothesizes that some, but not all, of the benefits received during wet floating would be achieved with dry floating, too.

From Los Angeles Times ● Feb. 18, 2026

Griffith hypothesizes that signals from TRPM8 and GluK2 might be somehow combined—in the spinal cord, brain, or both—to influence a mouse’s choices.

From Science Magazine ● Mar. 13, 2024

Oktay hypothesizes that those risks also may be mitigated in healthy women who delay menopause via ovarian tissue cryopreservation.

From Science Daily ● Feb. 6, 2024

How exactly that communication works isn't clear, but Schweikert hypothesizes that the system is working as a feedback system to keep the camouflage in check.

From Salon ● Aug. 22, 2023

Heckscher hypothesizes that this change in diet may help the veery return to North America in better shape, more capable of a longer breeding season.

From National Geographic ● Jul. 28, 2023

"We hypothesized that early initiation of LDL-C-lowering statins following type 2 diabetes diagnosis could be associated with a lower risk of dementia," said Doctor Ternhamar.

From Science Daily ● Sep. 8, 2026

Drawing on these findings, Dr. Snyder hypothesized that naturally occurring psychotic episodes were likely caused by high dopamine levels in the brain.

From The Wall Street Journal ● Jul. 28, 2026

Abatzoglou hypothesized the region’s link between wildfires and soil moisture could cause the mitigating effects of the preceding El Niño to linger longer.

From Los Angeles Times ● Jul. 22, 2026

He also hypothesized that Tesla could cut vehicle or FSD prices to make its EVs more affordable and attractive to consumers.

From MarketWatch ● Jul. 1, 2026

Properly called the Öpik–Oort cloud, it is named for the Estonian astronomer Ernst Öpik, who hypothesized its existence in 1932, and for the Dutch astronomer Jan Oort, who refined the calculations eighteen years later.

From "A Short History of Nearly Everything" by Bill Bryson

Musk has long sold his vision for Tesla to become the world’s most-valuable company, hypothesizing an eventual $30 trillion valuation on the strength of its robotics and AI products.

From The Wall Street Journal ● Apr. 8, 2026

My whole goal with this show was to capture a small sliver of the zeitgeist where people could be talking about something, hypothesizing and talking, and I knew that required a weekly release.

From Los Angeles Times ● Jun. 19, 2025

Thus, a controversy was sparked, with many scientists hypothesizing that non-cyanobacterial microorganisms must be responsible for the "missing" nitrogen fixation.

From Science Daily ● May 9, 2024

But they can also be longer, which means more effort, more information seeking and hypothesizing is needed, so uncertainty persists longer.

From Salon ● Oct. 21, 2023

No amount of your analyzing, criticizing, judging, or hypothesizing will bring the peace you are looking for.

From "Into Thin Air" by Jon Krakauer

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