IgG

American  

Immunology.

1. immunoglobulin G: a class of circulating antibodies predominant in serum, produced by plasma cells and memory cells in response to pathogens and other foreign substances, able to pass through the placental wall to the fetal circulation to impart immune defense for the period of infancy.

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Etymology

Origin of IgG

First recorded in 1960–65

Example Sentences

See Examples For:

IgG

Researchers also found tumor-specific IgG antibodies and persistent plasma cells in the bone marrow, clear signs of a durable, body-wide immune defense capable of preventing the cancer from returning.

From Science Daily ● Oct. 15, 2025

None of these differences, like IgG which is also in human breast milk, is necessarily harmful to humans.

From Salon ● Jan. 19, 2024

These discoveries provide important scientific evidence that improved immunity responses from both T cells and IgG antibodies contribute to greater and long-lasting protection of intranasal vaccines from COVID-19.

From Science Daily ● Jan. 10, 2024

IgG is transferred from the maternal circulation to the fetus via the placenta, protecting the fetus from infection and protecting the newborn for the first few months of its life.

From Textbooks ● Jun. 19, 2013

If the mother has a second Rh-positive child, IgG antibodies against Rh-positive blood mounted during this secondary response cross the placenta and attack the fetal blood, causing anemia.

From Textbooks ● Jun. 19, 2013