[im-yuh-noh-di-fish-uh n-see, ih-myoo-]

noun, plural im·mu·no·de·fi·cien·cies.

impairment of the immune response, predisposing to infection and certain malignancies.

Origin of immunodeficiency

First recorded in 1970–75; immuno- + deficiency
Related formsim·mu·no·de·fi·cient, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for immunodeficiency



a deficiency in or breakdown of a person's immune system
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for immunodeficiency

1969, from comb. form of immune + deficiency.

Online Etymology Dictionary, © 2010 Douglas Harper

immunodeficiency in Medicine


[ĭm′yə-nō-dĭ-fĭshən-sē, ĭ-myōō-]


A disorder or deficiency of the normal immune response.immune deficiency
Related formsim′mu•no•de•ficient adj.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

immunodeficiency in Science


[ĭm′yə-nō-dĭ-fĭshən-sē, ĭ-myōō′-]

The inability to produce a normal immune response, caused by an acquired or inherited disease.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.