immunoprecipitation

[im-yuh-noh-pri-sip-i-tey-shuhn, ih-myoo-]

noun

1. the separation of an antigen from a solution by the formation of a large complex with its specific antibody.

Word History and Origins

Origin of immunoprecipitation¹

First recorded in 1965–70; immuno- + precipitation

Example Sentences

They plan to use McPherson’s strategy to assess more antibodies against other targets, gauging performance across three common assays: immunoblot, immunoprecipitation and immunofluorescence.

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There are other methods researchers can try, too, such as coupling immunoprecipitation to mass spectrometry to see what proteins the antibody binds to4.

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Back in 2012, our first task on the master’s programme was to carry out a chromatin immunoprecipitation assay to detect protein–DNA interactions in the cell nucleus.

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Protein iBAQ values from the untagged control were subtracted from the tagged immunoprecipitation samples. h, Coomassie blue-stained gel of samples used for mass spectrometry analysis.

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To measure bits of amyloid coursing through the bloodstream, Yanagisawa and colleagues used a technique called immunoprecipitation with mass spectrometry, which deploysantibodies to bind and identify proteins.

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