irreversible

The contradictions raised by Wigner’s setup highlighted fundamental and compelling questions about what qualifies as a collapse-causing measurement and whether collapse is irreversible.

Some critics worry that reform would be like an on/off switch—suddenly and irreversibly changing America forever.

St. Paul's heart is pledged irrevocably and irreversibly to the Church.

For why should men do either, when all they can desire is irreversibly predestined?

As a race, the Southern Caucasian would be irreversibly doomed.

The real man is discovered, his worth is impartially weighed, his rank is irreversibly decreed.

To say nothing of the question of how much of Terra's best blood do you want to drain off, irreversibly and permanently?