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Jesus H. Christ

interjection Sometimes Offensive.
  1. (used as an oath or strong expression of disbelief, dismay, awe, disappointment, pain, etc.)
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Origin of Jesus H. Christ

1890–95, Americanism; the H probably < IHS or IHC, Greek abbreviation for Jesus, in which the H (the capital Gk letter eta) is reinterpreted as the English letter H
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018