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lipogenesis

British  
/ ˌlɪpəʊˈdʒɛnɪsɪs /

noun

  1. biochem the synthesis of fatty acids in the body from glucose and other substrates

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Example Sentences

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Interest in DGAT2 has grown because the enzyme plays a major role in de novo lipogenesis, the process the body uses to create fat in the liver.

From Science Daily ● May 27, 2026

In scientist-speak, “Compared with glucose, the hepatic metabolism of fructose favors lipogenesis, which may contribute to hyperlipidemia and obesity.”

From Salon ● Feb. 25, 2014

Although lipogenesis occurs in the cytoplasm, the necessary acetyl CoA is created in the mitochondria and cannot be transported across the mitochondrial membrane.

From Textbooks ● Jun. 19, 2013

The individual amino acids are broken down into pyruvate, acetyl CoA, or intermediates of the Krebs cycle, and used for energy or for lipogenesis reactions to be stored as fats.

From Textbooks ● Jun. 19, 2013

Excess acetyl CoA generated from excess glucose or carbohydrate ingestion can be used for fatty acid synthesis or lipogenesis.

From Textbooks ● Jun. 19, 2013

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