- to perform a lobotomy on.
- to make (someone or something) abnormally tranquil or sluggish.
Also especially British, lo·bot·o·mise.
Origin of lobotomize
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
Word Origin and History for lobotomize
Online Etymology Dictionary, © 2010 Douglas Harper