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major depressive disorder

American  
[may-jer-di-pres-iv-dis-awr-der] / ˈmeɪ dʒər dɪˈprɛs ɪv dɪsˈɔr dər /

noun

  1. Psychiatry. an affective disorder characterized by a sustained period of low mood, diminished self-esteem, and reduced interest in normally enjoyable activities.


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Spending less time in front of the television and more time on other activities could help prevent major depressive disorder, especially during middle age.

From Science Daily

Diagnoses of major depressive disorder were determined using the Mini International Neuropsychiatric Interview.

From Science Daily

"Taken together, these results may have important implications for the management of major depressive disorder," says Ciara Halvorson, a neuroscience PhD student at UVic and the study's first author.

From Science Daily

Earlier studies have shown that people diagnosed with major depressive disorder have lower levels of Reelin in their brains.

From Science Daily

Biohaven tumbles after its drug, BHV-7000, fails to meet the primary endpoint in a phase 2 trial for major depressive disorder.

From Barron's