major depressive disorder

American  

[may-jer-di-pres-iv-dis-awr-der] / ˈmeɪ dʒər dɪˈprɛs ɪv dɪsˈɔr dər /

noun

1. Psychiatry. an affective disorder characterized by a sustained period of low mood, diminished self-esteem, and reduced interest in normally enjoyable activities.

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Example Sentences

See Examples For:

major depressive disorder

Diagnoses of major depressive disorder were determined using the Mini International Neuropsychiatric Interview.

From Science Daily ● Feb. 12, 2026

Earlier studies have shown that people diagnosed with major depressive disorder have lower levels of Reelin in their brains.

From Science Daily ● Feb. 2, 2026

Antidepressants are typically prescribed for people with major depressive disorder.

From The Wall Street Journal ● Nov. 11, 2025

Behind its glassy doors is something rare: A community run by people with serious mental health conditions such as schizophrenia, bipolar disorder and major depressive disorder.

From Los Angeles Times ● Nov. 2, 2024

Another study of adolescents ages 12 to 17 who participated in the 2021 National Survey on Drug Use and Health found that 20% of them had experienced major depressive disorder in the past year.

From Los Angeles Times ● Oct. 1, 2024