make a difference
Distinguish or discriminate. This phrase appears in the Bible (Leviticus 11:47): “To make a difference between the unclean and the clean.” [Late 1500s]
Also, make the difference. Cause a change in effect, change the nature of something, as in His score on this test will make the difference between passing and failing, or These curtains sure make a difference in the lighting.
Be important, matter, as in Her volunteer work made a difference in many lives. The antonym of this usage is make no difference, as in It makes no difference to me if we go immediately or in an hour. This usage appeared long ago in slightly different versions. Miles Coverdale's translation of the Bible of 1535 had it is no difference, and the converse, it makes great difference, was first recorded about 1470.
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How to use make a difference in a sentence
Genetics alone does not an eating disorder make, generally speaking, and Bulik points out that environment still plays a role.
And yes, our values include tolerance of those who wish to make fun of religion.Ayaan Hirsi Ali: Our Duty Is to Keep Charlie Hebdo Alive|Ayaan Hirsi Ali|January 8, 2015|DAILY BEAST
The court ruled she lacked the maturity to make her own medical decisions.
ROME — What does it take for a Hollywood A-lister to get a private audience with Pope Francis?Pope Francis Has the Pleasure of Meeting Angelina Jolie for a Few Seconds|Barbie Latza Nadeau|January 8, 2015|DAILY BEAST
Again, the difference can seem subtle and sound more like splitting hairs, but the difference is important.
And to tell the truth, she couldn't help wishing he could see, so he could make the game livelier.The Tale of Grandfather Mole|Arthur Scott Bailey
She did not need a great cook-book; She knew how much and what it took To make things good and sweet and light.
Now-a-days it is the bankrupt who flouts, and his too confiding creditors who are jeered and laughed at.Glances at Europe|Horace Greeley
Now this setting up of an orderly law-abiding self seems to me to imply that there are impulses which make for order.Children's Ways|James Sully
Give a sweet savour, and a memorial of fine flour, and make a fat offering, and then give place to the physician.The Bible, Douay-Rheims Version|Various