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Synonyms

manic-depressive

American  
[man-ik-di-pres-iv] / ˈmæn ɪk dɪˈprɛs ɪv /

adjective

  1. having or experiencing bipolar disorder.


noun

  1. a person with this disorder.

manic-depressive British  

adjective

  1. denoting a mental disorder characterized either by an alternation between extreme euphoria and deep depression (bipolar manic-depressive disorder or syndrome) or by depression on its own or (rarely) by elation on its own (unipolar disorder)

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

noun

  1. a person afflicted with this disorder Compare cyclothymia

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of manic-depressive

First recorded in 1900–05

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Much has changed since Tiberius and John Law and Jefferson Davis, but not the manic-depressive nature of speculative markets.

From The Wall Street Journal • Dec. 12, 2025

I know only that my mother, while still in fourth grade, watched Tomoyo go through a manic-depressive episode.

From Seattle Times • May 14, 2023

Iris, stately in her silk trousers and Nehru jacket, introducing herself in the group meetings as “a manic-depressive of 27 years’ standing.”

From New York Times • Jan. 6, 2021

Also important: This way he doesn’t see me cowering in the corner, ashamed of who and what I am: a manic-depressive, perimenopausal woman.

From Slate • Aug. 4, 2020

Acquaintances remember him as a socially awkward man-child with an outrageous sense of humor and a squirrelly, almost manic-depressive personality.

From "Into the Wild" by Jon Krakauer