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mast cell

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noun Biology.
a large granular cell, common in connective tissue, that produces heparin, histamine, and serotonin.
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Origin of mast cell

1885–90; partial translation of German Mastzelle, equivalent to Mast fattening of animals for slaughter, mast2 + Zelle cell
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use mast cell in a sentence

  • The substance of the mast cell granulations is also crystalline in some species of animals.

  • The mast cell granulations are stained pure blue, the eosinophil red, the neutrophil in mixed colour.

  • Evidently part of the dyed mast cell substance is dissolved and retained in the immediate neighbourhood.

British Dictionary definitions for mast cell

mast cell

noun
a type of granular basophil cell in connective tissue that releases heparin, histamine, and serotonin during inflammation and allergic reactions

Word Origin for mast cell

C19: from mast ², on the model of German Mastzelle
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Scientific definitions for mast cell

mast cell
[ măst ]

A granular cell found in body tissue, especially connective tissue, that activates inflammation by releasing a variety of chemical substances including histamine, tumor necrosis factor, and interleukins. Mast cells have membrane receptors that bind to bacteria, triggering the release of inflammatory mediators from the mast cell's cytoplasmic granules. Mast cells also play an important role in allergic reactions. Other receptors on their membranes bind to specific antibodies that, combined with certain antigens, initiate granular release of chemical mediators that cause allergic signs and symptoms.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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