- a large granular cell, common in connective tissue, that produces heparin, histamine, and serotonin.
Origin of mast cell
1885–90; partial translation of German Mastzelle, equivalent to Mast fattening of animals for slaughter, mast2 + Zelle cell
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- a type of granular basophil cell in connective tissue that releases heparin, histamine, and serotonin during inflammation and allergic reactions
Word Origin for mast cell
C19: from mast ², on the model of German Mastzelle
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
- A cell found in connective tissue that contains numerous basophilic granules and releases substances such as heparin and histamine in response to injury or inflammation of bodily tissues.labrocyte mastocyte
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
- A granular cell found in body tissue, especially connective tissue, that activates inflammation by releasing a variety of chemical substances including histamine, tumor necrosis factor, and interleukins. Mast cells have membrane receptors that bind to bacteria, triggering the release of inflammatory mediators from the mast cell's cytoplasmic granules. Mast cells also play an important role in allergic reactions. Other receptors on their membranes bind to specific antibodies that, combined with certain antigens, initiate granular release of chemical mediators that cause allergic signs and symptoms.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.