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Synonyms

predispose

American  
[pree-di-spohz] / ˌpri dɪˈspoʊz /

verb (used with object)

  • predisposes,
    present (3rd person singular)
  • predisposed,
    past participle,  past
  • predisposing
    present participle
  1. to give an inclination or tendency to beforehand; make susceptible.

    Genetic factors may predispose human beings to certain metabolic diseases.

    Synonyms:
    prepare, prearrange
  2. to render subject, susceptible, or liable.

    The evidence predisposes him to public censure.

  3. to dispose beforehand.

    Synonyms:
    incline, bias
  4. Archaic. to dispose of beforehand, as in a will, legacy, or the like.


verb (used without object)

  • predisposes,
    present (3rd person singular)
  • predisposed,
    past participle,  past
  • predisposing
    present participle
  1. to give or furnish a tendency or inclination.

    an underground job that predisposes to lung infection.

predispose British  
/ ˌpriːdɪˈspəʊz /

verb

  1. to incline or make (someone) susceptible to something beforehand

  2. law to dispose of (property, etc) beforehand; bequeath

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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Etymology

Origin of predispose

First recorded in 1640–50; pre- + dispose

Explanation

Predispose means to have a tendency toward something. Some people believe that just being born in Canada will predispose you to love ice hockey. Many situations or events can predispose you to have a particular reaction, opinion, or feeling. Being bitten by a dog as a child could predispose you to having a fear of dogs. Having ancestors with great athletic ability might predispose you to enjoy running. If you want to predispose your father to liking your new boyfriend, be sure to tell him about volunteering at the food bank and leave out the bits about his arrest and dropping out of school.

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Vocabulary lists containing predispose

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Recognizing this, some oncologists have begun administering drugs with restraint rather than abandon, aiming to keep the cancer in check rather than creating conditions that predispose to the rapid growth of resistant cells.

From The Wall Street Journal Apr. 20, 2026

"The whole team undertakes a standardized warm-up that addresses a number of physical concerns that predispose our female athletes to ACLs," she said.

From BBC Jun. 30, 2025

Their goal was to pinpoint what biological conditions might predispose some people to the problem.

From Los Angeles Times Mar. 12, 2025

Nothing in her environment would predispose her to cancer, except for being in close proximity to the fires.

From Slate Jan. 16, 2025

Attitudes such as these certainly predispose one to innumeracy.

From "Innumeracy: Mathematical Illiteracy and Its Consequences" by John Allen Paulos

The condition turns up in 10% to 20% of people in their 70s, and predisposes them to blood cancer and, surprisingly, heart disease, likely driven by the inflammation these rogue cells provoke.

From The Wall Street Journal Apr. 20, 2026

Studies show that adding sugar to any food for babies or small children predisposes them to having a sweet tooth.

From Salon Apr. 25, 2024

This predisposes them to developing the disease but in itself is not symptomatic.

From Science Daily Apr. 22, 2024

Perhaps spending a premium to see a movie in person, and planning ahead, predisposes people to savor the experience.

From Los Angeles Times Dec. 1, 2023

Cold weather only predisposes to the infection, and after it has occurred it is sure to run its course.

From Psychotherapy by James J. (James Joseph) Walsh

Certain breeds are predisposed to heart or orthopedic issues, for example, that can be expensive to treat.

From MarketWatch Sep. 15, 2026

But he was also predisposed to remedies that would not require what he described as “a priori, the sacrifice of the energy value of oil, gas, and coal.”

From Salon Jun. 26, 2026

"Exosomes are used to communicate with and activate surrounding cells, and we have now identified a defect in both the production and the quality of exosomes in cells that we know are predisposed to Alzheimer's."

From Science Daily Nov. 25, 2025

What's more, With Love, Meghan was never going to change opinions of those who are already, for whatever reason, predisposed against her - just as her new podcast series is unlikely to.

From BBC Apr. 6, 2025

The cases described, on the other hand, were predisposed to gross lapses in reality contact and extreme weakness in impulse control during periods of heightened tension and disorganization.

From "In Cold Blood" by Truman Capote

Fifteen potentially harmful and predisposing variants in the same RNF207 and PRKAA2 genes, which had been identified in dogs, were discovered in humans.

From Science Daily Sep. 22, 2023

“The difference is likely due to a combination of stress and inflammation, arising from predisposing factors and the way this virus biologically interacts with the cardiovascular system.”

From Seattle Times Oct. 26, 2022

Many species of Sorbus have a small population size, predisposing them to threatening events.

From BBC Sep. 26, 2021

“Climate change is predisposing the fuels into drier conditions,” Stephens said.

From Los Angeles Times Oct. 6, 2020

Was there anything about the Chinese environment predisposing toward Confucian philosophy and cultural conservatism, which may also have profoundly affected history?

From "Guns, Germs, and Steel: The Fates of Human Societies" by Jared M. Diamond

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