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Synonyms

predispose

American  
[pree-di-spohz] / ˌpri dɪˈspoʊz /

verb (used with object)

  • predisposes,
    present (3rd person singular)
  • predisposed,
    past participle,  past
  • predisposing
    present participle
  1. to give an inclination or tendency to beforehand; make susceptible.

    Genetic factors may predispose human beings to certain metabolic diseases.

    Synonyms:
    prepare, prearrange
  2. to render subject, susceptible, or liable.

    The evidence predisposes him to public censure.

  3. to dispose beforehand.

    Synonyms:
    incline, bias
  4. Archaic. to dispose of beforehand, as in a will, legacy, or the like.


verb (used without object)

  • predisposes,
    present (3rd person singular)
  • predisposed,
    past participle,  past
  • predisposing
    present participle
  1. to give or furnish a tendency or inclination.

    an underground job that predisposes to lung infection.

predispose British  
/ ˌpriːdɪˈspəʊz /

verb

  1. to incline or make (someone) susceptible to something beforehand

  2. law to dispose of (property, etc) beforehand; bequeath

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

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Etymology

Origin of predispose

First recorded in 1640–50; pre- + dispose


Explanation

Predispose means to have a tendency toward something. Some people believe that just being born in Canada will predispose you to love ice hockey. Many situations or events can predispose you to have a particular reaction, opinion, or feeling. Being bitten by a dog as a child could predispose you to having a fear of dogs. Having ancestors with great athletic ability might predispose you to enjoy running. If you want to predispose your father to liking your new boyfriend, be sure to tell him about volunteering at the food bank and leave out the bits about his arrest and dropping out of school.

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Vocabulary lists containing predispose

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Research by UC San Francisco’s Sharon suggests migraine headaches predispose people to BPPV, by causing crystals to dislodge from their normal location.

From The Wall Street Journal ● Apr. 15, 2026

"The whole team undertakes a standardized warm-up that addresses a number of physical concerns that predispose our female athletes to ACLs," she said.

From BBC ● Jun. 30, 2025

Nothing in her environment would predispose her to cancer, except for being in close proximity to the fires.

From Slate ● Jan. 16, 2025

It was a pretty standard effort to identify people whose views might predispose them against their client’s contentions.

From Salon ● Feb. 23, 2024

Attitudes such as these certainly predispose one to innumeracy.

From "Innumeracy: Mathematical Illiteracy and Its Consequences" by John Allen Paulos

Nor does it hurt that the extraordinary popularity of the Harry Potter movies predisposes much of the audience to sympathy and affection.

From The Wall Street Journal ● Mar. 13, 2026

This predisposes them to developing the disease but in itself is not symptomatic.

From Science Daily ● Apr. 22, 2024

Perhaps spending a premium to see a movie in person, and planning ahead, predisposes people to savor the experience.

From Los Angeles Times ● Dec. 1, 2023

"Pollutants make you more allergic in general and this can trigger eczema, being an allergic individual predisposes you to developing eczema compared with a non-allergic person."

From Salon ● Jun. 3, 2023

Here deformity does not prevent marriage, but predisposes to sterility through birth difficulty.

From Degeneracy Its Causes, Signs and Results by Eugene S. Talbot

Many Americans are predisposed to think that wealthy people earned their money and that it’s churlish to try to take it away from them.

From Slate ● Nov. 3, 2026

If a director sits on only one board and is well paid for that job, for example, are they predisposed to fall in line?

From The Wall Street Journal ● Oct. 23, 2026

Certain breeds are predisposed to heart or orthopedic issues, for example, that can be expensive to treat.

From MarketWatch ● Sep. 15, 2026

Among participants assigned to the low-carb diet, those who were genetically predisposed to higher LDL cholesterol were more likely to experience an increase.

From Science Daily ● Aug. 26, 2026

Charlie and his partners had done this often enough, and had had enough success, to know that the markets were predisposed to underestimating the likelihood of dramatic change.

From "The Big Short" by Michael Lewis

There may also be "predisposing factors", such as trauma, issues from early childhood, or negative self-belief, that can make it harder to curb your use, she says.

From BBC ● Aug. 8, 2026

“Inadequate nutrition, particularly vitamin A deficiency, can impair the lining of the digestive tract, predisposing birds to inflammation and secondary illness.”

From Los Angeles Times ● Apr. 20, 2026

Fifteen potentially harmful and predisposing variants in the same RNF207 and PRKAA2 genes, which had been identified in dogs, were discovered in humans.

From Science Daily ● Sep. 22, 2023

“The difference is likely due to a combination of stress and inflammation, arising from predisposing factors and the way this virus biologically interacts with the cardiovascular system.”

From Seattle Times ● Oct. 26, 2022

Was there anything about the Chinese environment predisposing toward Confucian philosophy and cultural conservatism, which may also have profoundly affected history?

From "Guns, Germs, and Steel: The Fates of Human Societies" by Jared M. Diamond

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