monoclonal antibody

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noun Biotechnology.

antibody produced by a laboratory-grown cell clone, either of a hybridoma or a virus-transformed lymphocyte, that is more abundant and uniform than natural antibody and is able to bind specifically to a single site on almost any chosen antigen or reveal previously unknown antigen sites: used as an analytic tool in scientific research and medical diagnosis and potentially important in the treatment of certain diseases. Abbreviation: MAb

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Origin of monoclonal antibody

First recorded in 1970–75

Words nearby monoclonal antibody

monoclinal, monocline, monoclinic, monoclinous, monoclonal, monoclonal antibody, monoclonality, monocoque, monocot, monocotyledon, monocotyledonous

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use monoclonal antibody in a sentence

She said the utility of vaccines, monoclonal antibody treatments and some coronavirus tests “could be undermined” if there is a big enough change caused by a new coronavirus strain.
New coronavirus variants accelerate race to make sure vaccines keep up|Carolyn Y. Johnson, Laurie McGinley, Joel Achenbach|January 26, 2021|Washington Post
Mutations could limit the efficacy of vaccines or therapeutic drugs such as monoclonal antibodies.
CDC warns highly transmissible coronavirus variant to become dominant in U.S.|Joel Achenbach|January 15, 2021|Washington Post
While I feel ok, on my doctor's advice I'm on my way to a local hospital for monoclonal antibody treatment.
The Capitol outbreak shows one vaccine dose may not fully shield against the coronavirus|Umair Irfan|January 12, 2021|Vox
The rise of variants also could limit the efficacy of monoclonal antibody treatments because such therapeutics are very narrowly focused and potentially could be eluded by a single mutation.
CDC foresees spread in U.S. of highly contagious coronavirus variant|Joel Achenbach, Ben Guarino|January 6, 2021|Washington Post

The hospital also has begun to offer infusions of remdesivir and monoclonal antibodies, therapies for covid-19, to outpatients.
Inside a Rhode Island field hospital, preparing for the worst of the pandemic|Lenny Bernstein|December 26, 2020|Washington Post

British Dictionary definitions for monoclonal antibody

monoclonal antibody

/ (ˌmɒnəʊˈkləʊnəl) /

noun

an antibody, produced by a single clone of cells grown in culture, that is both pure and specific and is capable of proliferating indefinitely to produce unlimited quantities of identical antibodies: used in diagnosis, therapy, and biotechnology

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012