nalidixic acid

[ney-li-dik-sik, ney-]

noun

Pharmacology.

1. a substance, C 1 2 H 1 2 N 2 O 3 , that has antibacterial activity against many susceptible Gram-negative organisms, especially used in the treatment of urinary tract infections.

Word History and Origins

Origin of nalidixic acid¹

1960–65; by shortening and rearrangement of naphthyridine and carboxylic acid, components of its chemical name

Example Sentences

However, 50 percent of infections resistant to the fluoroquinolone drug nalidixic acid were caused by Salmonella enteritidis, the most common salmonella type.

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Resistance to nalidixic acid -- used in laboratory testing for resistance -- is related to decreased susceptibility to a widely used fluoroquinolone drug ciprofloxacin, the CDC said in its release.

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