naloxone

[nuh-lok-sohn, nal-uhk-sohn]

noun

Pharmacology.

1. an opioid antagonist, C 19 H 21 NO 4 , used to reverse the acute respiratory depression that occurs with opioid overdose.

naloxone

/ nəˈlɒksəʊn /

noun

1. a chemical substance that counteracts the effects of opiates by binding to opiate receptors on cells

Word History and Origins

Origin of naloxone¹

First recorded in 1960–65; by shortening and rearrangement of dihydroxy-, morphinan-, and -one, components of its chemical name

Word History and Origins

Origin of naloxone¹

C20: from N-al ( lylnor ) ox ( ymorph ) one, the chemical name

Example Sentences

MLB emergency medical procedures now require that naloxone be stored in clubhouses, weight rooms, dugouts and umpire dressing rooms at all ballparks.

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The department also recommends carrying naloxone, which can reverse 7-OH toxicity as well as opioid overdoses.

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The Riverside University Health System recommended that individuals carry naloxone to treat someone overdosing on fentanyl and avoid using carfentanil even in small doses due to the unpredictability and potency of the substance.

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Separately, an update from the city's mayor, Brandon Scott, offered advice to residents who use drugs, including to never use alone and to carry naloxone - which can reverse or reduce the effects of an overdose.

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Slated for abolition is the National Institute for Drug Abuse, the research group at the National Institutes of Health that helped develop the nasal version of naloxone.

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