neoadjuvant

American  

[nee-oh-aj-uh-vuhnt] / ˌni oʊˈædʒ ə vənt /

adjective

Medicine/Medical.

1. utilizing drugs, radiation therapy, or other means of supplemental treatment before cancer surgery or other primary cancer treatment.

   Her neoadjuvant therapy included hormones and chemo, which shrank the tumor prior to its surgical removal.

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Etymology

Origin of neoadjuvant

First recorded in 1980–85; neo- ( def. ) + adjuvant ( def. )

Example Sentences

"This study builds on the standard-of-care neoadjuvant chemoimmunotherapy treatment and supports perioperative nivolumab as an effective approach that reduces the risk of lung cancer relapse," said principal investigator Tina Cascone, M.D.,

From Science Daily • May 15, 2024

"This study shows that a combination of neoadjuvant and adjuvant durvalumab offers benefit for patients and may have the potential to change standard-of-care for patients with resectable non-small cell lung cancer," Heymach said.

From Science Daily • Oct. 23, 2023

For resectable NSCLC, previous studies have shown some benefit from using adjuvant or neoadjuvant immunotherapy, but Heymach explained the benefits have been modest so far.

From Science Daily • Oct. 23, 2023

"Our goal is to increase cures for lung cancer. Throughout decades of research with adjuvant and neoadjuvant chemotherapy, we only succeeded in increasing cures by around 5%,"

From Science Daily • Oct. 23, 2023

Still, the race is on in both the adjuvant and neoadjuvant setting, where treatment precedes surgery.

From Reuters • Jul. 6, 2018