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neural tube defect

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noun Pathology.
  1. any of a group of congenital abnormalities involving the brain and spinal cord, including spina bifida and meningocele, caused by failure of the neural tube to close properly during embryonic development.
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Origin of neural tube defect

First recorded in 1885–90
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018